TOXICOLOGY

LEARNING OUTCOMES

The student, after the end of the course, should:
● be familiar with the basic principles of toxicokinetic, toxicodynamic, clinical toxicology and
analytical toxicology.
● understand the actions of environmental parameters that may constitute danger to plants, animals and humans.
● Know the toxicity of substances, metals and drugs and the way of poisoning treatment.

SYLLABUS

● Introduction. Principles of Toxicology. Subject and branches of toxicology.
● Categories and classification of toxic. Absorption, distribution and excretion of toxins substances, Toxicokinetic.
● Medicines (paracetamol, salicylates, benzodiazepines, barbiturates, tricyclics antidepressants)
● Drugs (cannabinoids, opiates, stimulants, hallucinogens)
● Doping categories. Anabolic steroids, diuretics, adrenergic agonists, hormones, stimulants, drugs. Laboratory check. Gene doping
● Pesticides. Toxic effects of pesticides. Residues of toxic compounds in food / water
● Veterinary medicines. Toxic effects of poisons and terrestrial toxins of animals.
● Toxic effects of plants, fungi and algae.
● Toxic effects of solvents and vapors (halogenated hydrocarbons, its monoxide carbon, carbon dioxide, hydrogen cyanide). Ethanol (pharmacokinetic, measurement in biological fluids and exhaled air, toxicity).
● Toxic effects of metals (heavy metals).
● Toxic effects of radiation and radioactive materials.
● Modern methods of analytical toxicology (immunochemistry, chromatography, Spectrophotometry).